Improved Synthesis of 5'-Deoxy-5'-adenosineacetic Acid

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ATTEMPTED SYNTHESIS OF 5' - DEOXY - 5' - PHOSPHONO - ISOCYTIDINE SYNTHESIS OF PHOSPHONIC ACID DERIVATIVES OF ACYCLO - NUCLEOSIDES. PREPARATION OF 1- ?- D- ARABINOFURANOSYL PYRIMIDINES

The synthesis of 5' - deoxynucleoside 5' - phosphonates which contains a 5' - CP bond in place of the 5' -COP bond of the naturally occuring nucleotides is described. The preparation of phosphonate derivatives of acyclo - nucleosides and a simple method for the conversion of 1-? -D-ribofuranosyl pyrimidines to the corresponding 1-? -D-arabinofuranosyl pyrimidines are also explained

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5-Aminosalicylic acid (5-ASA) is currently prepared by electrochemical reduction of 5-nitrosalicylic acid (5-NSA) in acidic media. In this work, electrolytic reduction of 5-NSA in alkaline media is presented. Reactionconditions and parameters such as anode and cathode electrodes, electrolyte type, reaction time, temperature,current, and the pH for isolation of product are investigated. The yiel...

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attempted synthesis of 5' - deoxy - 5' - phosphono - isocytidine synthesis of phosphonic acid derivatives of acyclo - nucleosides. preparation of 1- ?- d- arabinofuranosyl pyrimidines

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ژورنال

عنوان ژورنال: Chemical and Pharmaceutical Bulletin

سال: 1983

ISSN: 0009-2363,1347-5223

DOI: 10.1248/cpb.31.2126